前田先生（立命館大）と久木先生（大阪大）の共著論文

前田大光 先生（立命館大）と久木一朗 先生（大阪大）の共著論文が掲載されました。

Doubly N-Methylated Porphyrinoids

Wakana Naito, Nobuhiro Yasuda, Tatsuki Morimoto, Yasuteru Shigeta, Hikaru Takaya, Ichiro Hisaki, and Hiromitsu Maeda*

Org. Lett. 2016, 18, 3006–3009.
DOI: 10.1021/acs.orglett.6b01377

Abstract

Chirality-induced aromatic π-electronic macrocycles, porphyrin and corroles, were synthesized through doubly inner N-methylation through multistep and one-pot reactions, respectively. The exact structures of doubly N-methylated porphyrin and corroles were revealed by single-crystal synchrotron X-ray analysis, exhibiting two N-methyl groups located on neighboring pyrrole rings in up/down conformations. These doubly inner N-substitutions of the π-electronic macrocycles induced distorted geometries, resulting in chiroptical properties after optical resolutions.